CEFOZONE 1g- (Sulbactam & Cefoperazone)- Injection solution- TAJ PHARMA
Cefoperazone-Sulbactam for treatment of intra-abdominal infections
The combination of Cefoperazone Sodium and Sulbactam Sodium is indicated for the treatment of the following infections caused by susceptible organisms.
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Respiratory tract infections (Upper and Lower), Urinary
Tract Infections, Peritonitis, Cholecystitis, Cholangitis
and other intra-abdominal infections, Bacterial sinusitis,
Meningitis, Skin and soft tissue infections, Bone and Joint
infections, Pelvic Inflammatory disease - endometritis,
gonorrhea and other infections of the genital tract.
DOSAGE AND ADMINISTRATION
Adults:
The usual adult dose of the combination is 2 to 4 g/day (i.e, 1-2 g/day each of Cefoperazone and Sulbactam) given IV or IM in equally divided doses every 12 hours.
In severe or refractory infections the daily dosage may be increased to 8g (i.e, 4g/day each of Cefoperazone and Sulbactam) given IV in equally divided doses every 12 hours. The recommended maximum daily dosage of Sulbactam is 4g (8g of the combination).
Dosage regimens should be adjusted in patients with marked decrease in renal function.
Children:
The usual dosage in children is 40-80mg/kg/day (20 to 40 mg/kg/day each of Cefoperazone and Sulbactam) every six to twelve hours. In serious or refractory infections, these dosages may be increased up to 160 mg/kg/idea of the combination. (i.e., 80 mg/kg/day each of Cefoperazone and Sulbactam) every six to twelve hours.
STORAGE
Cefoperazone-Sulbactam for treatment of intra-abdominal infections
The combination of Cefoperazone Sodium and Sulbactam Sodium is indicated for the treatment of the following infections caused by susceptible organisms.
DOSAGE AND ADMINISTRATION
Adults:
The usual adult dose of the combination is 2 to 4 g/day (i.e, 1-2 g/day each of Cefoperazone and Sulbactam) given IV or IM in equally divided doses every 12 hours.
In severe or refractory infections the daily dosage may be increased to 8g (i.e, 4g/day each of Cefoperazone and Sulbactam) given IV in equally divided doses every 12 hours. The recommended maximum daily dosage of Sulbactam is 4g (8g of the combination).
Dosage regimens should be adjusted in patients with marked decrease in renal function.
Children:
The usual dosage in children is 40-80mg/kg/day (20 to 40 mg/kg/day each of Cefoperazone and Sulbactam) every six to twelve hours. In serious or refractory infections, these dosages may be increased up to 160 mg/kg/idea of the combination. (i.e., 80 mg/kg/day each of Cefoperazone and Sulbactam) every six to twelve hours.
STORAGE
Intravenous
Before reconstitution: Store below 25°C.
Reconstituted solutions are stable for 7 days at 2-8°C and for 24 hours at 8-25°C. All unused portions after the above stated time periods should be discarded.
Reconstituted solutions are stable for 7 days at 2-8°C and for 24 hours at 8-25°C. All unused portions after the above stated time periods should be discarded.
